Tag: Disease

Protein That Regulates Brain Cell Connections Could Be New Target for Treating Alzheimer’s Disease

In experiments with a protein called Ephexin5 that appears to be elevated in the brain cells of Alzheimer’s disease patients and mouse models of the disease, Johns Hopkins researchers say removing it prevents animals from developing Alzheimer’s characteristic memory losses. In a report on the studies, published online March 27 in The Journal of Clinical Investigation, the researchers say the findings could eventually advance development of drugs that target Ephexin5 to prevent or treat symptoms of the disorder.

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16 Aplastic Anemia Patients Free Of Disease After Bone Marrow Transplant and Chemo

Physicians at the Johns Hopkins Kimmel Cancer Center report they have successfully treated 16 patients with a rare and lethal form of bone marrow failure called severe aplastic anemia using partially matched bone marrow transplants followed by two high doses of a common chemotherapy drug. In a report on the new transplant-chemo regimen, published online Dec. 22, 2016, in Biology of Blood and Marrow Transplantation, the Johns Hopkins team says that more than a year after their transplants, all of the patients have stopped taking immunosuppressive drugs commonly used to treat the disorder and have no evidence of the disease.

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Women may have better verbal memory skills than men during early stages of Alzheimer’s disease

Women may have better verbal memory skills than men even when their brains show the same level of problems metabolizing glucose, which occurs in people with Alzheimer’s disease, according to research published in the October 5, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
News-Medical.Net Women’s Health News Feed

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