Tag: Disease

16 Aplastic Anemia Patients Free Of Disease After Bone Marrow Transplant and Chemo

Physicians at the Johns Hopkins Kimmel Cancer Center report they have successfully treated 16 patients with a rare and lethal form of bone marrow failure called severe aplastic anemia using partially matched bone marrow transplants followed by two high doses of a common chemotherapy drug. In a report on the new transplant-chemo regimen, published online Dec. 22, 2016, in Biology of Blood and Marrow Transplantation, the Johns Hopkins team says that more than a year after their transplants, all of the patients have stopped taking immunosuppressive drugs commonly used to treat the disorder and have no evidence of the disease. read more

Women may have better verbal memory skills than men during early stages of Alzheimer’s disease

Women may have better verbal memory skills than men even when their brains show the same level of problems metabolizing glucose, which occurs in people with Alzheimer’s disease, according to research published in the October 5, 2016, online issue of Neurology®, the medical journal of the American Academy of Neurology.
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New Evidence: How Amino Acid Cysteine Combats Huntington’s Disease

Researchers at Johns Hopkins Medicine report they have identified a biochemical pathway linking oxidative stress and the amino acid cysteine in Huntington’s disease. The findings, described in last week’s issue of the Proceedings of the National Academy of of Sciences, provide a mechanism through which oxidative stress specifically damages nerve cells in Huntington’s disease, an inherited and fatal neurodegenerative disorder. read more

Genetically Engineered Mice Suggest New Model for How Alzheimer’s Disease Causes Dementia

Using a novel, newly developed mouse model that mimics the development of Alzheimer’s disease in humans, Johns Hopkins researchers say they have been able to determine that a one-two punch of major biological “insults” must occur in the brain to cause the dementia that is the hallmark of the disease. A description of their experiments is published online in the journal Nature Communications. read more